Canada’s Milos Raonic, who has been battling a knee injury, pulled out of the French Open on Sunday.
The French Open starts in Paris next Sunday.
“It is with a heavy heart that I am withdrawing from @rolandgarros,” wrote the 27-year-old on Twitter.
“I have many great memories there, but I know I need to continue working hard to put myself in the best position when I step out on the court.
“Thank you all for your support and see you soon on the grass.”
The world number 22, a Wimbledon runner-up in 2016 and who reached the French Open quarter-finals in 2014, had withdrawn from the Monte Carlo Masters in April with a knee injury before his third round match.
He returned for the Madrid Masters where he lost in the third round to compatriot Denis Shapovalov.